BACKGROUND: The Escherichia coli chaperonin GroEL subunit consists of three domains linked via two hinge regions. and each domain is responsible for a specific role in the functional mechanism. Here. we have used circular permutation to study the structural and functional characteristics of the GroEL subunit. https://www.spidertattooz.com/OPI-GelColor-The-Color-That-Keeps-On-Giving-0-5-oz-HPJ07-p22791/