You will find there's release of norepinephrine from your descending inhibitory bulbospinal neurons that binds to alpha-2-receptors while in the dorsal horn to minimize afferent suffering transmission and deliver analgesia. Therefore, prescription drugs like clonidine that focus on alpha-two receptors can impact the transmission of ache. Jun 10, 2024 https://silask494otx4.myparisblog.com/profile